var fDesc=new Array(); fDesc[0] = "Is a program for the analysis of enzyme-kinetic data.

The velocity (v) of enzyme-catalyzed reactions is hyperbolically related to the substrate concentration ([S]) through the Michaelis-Menten equation:

v = Vmax.[S]/(Km [S])

where Vmax and Km are kinetic constants characteristic of the particular enzyme and substrate.

These constants are estimated in experiments in which [S] is varied and v measured.

They are usually extracted by some linear transformation of the data such as the Lineweaver-Burk or Hanes plots. These transformations are unsatisfactory as they can result in artificial weighting of the data leading to erroneous estimates of Vmax and Km."; function tShowHide(id, show) { var s = document.getElementById("desc"); if ((s.innerHTML.length<=212 || show==1) && show!=2) { s.innerHTML = fDesc[id]; if (document.getElementById('m1')) document.getElementById('m1').style.display='none'; if (document.getElementById('m2')) document.getElementById('m2').style.display='none'; if (document.getElementById('more_txt')) document.getElementById('more_txt').style.display='inline'; } else { s.innerHTML = ''; } }